Allergy Research Group®

 Matrixx™

Matrixx™ - 180 Capsules

Matrixx™ is a formula specifically designed to support the elastin and glycosaminoglycan components of connective tissue.* The term connective tissue refers to the various types of tissue that make up the joints, tendons, ligaments, vasculature, even the "web" that holds all cells together.  Matrixx™ contains the building blocks of connective tissue including key nutrients that are difficult to obtain, even in the highest quality of diets, and includes both glucosamine sulfate and n-acetyl-d-glucosamine, vital minerals and key amino acids. Hawthorne extract supports blood and lymphatic flow, which carry additional nutrients in the formula to areas where they are needed to support the production of healthy connective tissue, or to be used by the body during the inflammatory process.*

Hawthorne berry contains flavonoids and OPC's (oligomeric proanthocyanidins) which promote connective tissue stability and antagonize the actions of the enzyme elastase, which breaks down connective tissue. Hawthorne also has  vasodilatory and circulatory stimulating effects, which help bring nutrients to tissue and remove waste products from localized areas, such as areas of injury or inflammation. This is especially important in cartilage, which is largely avascular and receives its blood supply through diffusion. Furthermore, flavonoids activate proline hydroxylase, an enzyme necessary for healthy collagen biosynthesis.*

L-Proline, L-Lysine and Vitamin C are two amino acids and one vitamin central in connective tissue health. Proline is a major building block of the connective tissue proteins collagen and elastin.  One fourth to one third of the collagen reinforcement rods, for example, are made up of proline. Therefore, it is easy to understand how important it is, for the optimum stability of our blood vessels and our body in general, to get an optimum amount of proline in our diet. Proline can be synthesized by the body, but the amounts synthesized are frequently too little, particularly in those at an increased risk for cardiovascular disease. Lysine is an essential amino acid, which means that the body cannot synthesize this amino acid at all. Lysine has the remarkable property of augmenting collagen synthesis while preventing inappropriate cross-link formation. Lysine, like proline, is an important building block of collagen and of other connective tissue molecules and its intake helps to stabilize the blood vessels and the other organs in the body. For optimum strength of the collagen molecules, their building blocks lysine and proline need to be biochemically modified to hydroxylysine and hydroxyproline. Vitamin C is the most effective biocatalyst to accomplish this "hydroxylation" reaction, thereby providing optimum strength to the connective tissue.*

Trace minerals play a central role in connective tissue health;  therefore, key trace minerals are found in Matrixx™, such as silicon, boron, copper, zinc, and manganese. *

Horsetail extract provides a rich source of naturally occurring and readily absorbed silicon, a trace mineral critical for connective tissue and skeletal development and maintenance. *

Boron plays an exciting role in osseous health by supporting the regulation of Vitamin D, Phosphorus, Calcium, Magnesium and hormone levels, with a net effect of opposing osseous mineral loss and promoting osseous anabolism and protection. Lysyl oxidase (protein-lysine 6-oxidase) is a copper dependant enzyme (cupro-enzyme) that is essential for stabilization of extra-cellular matrixes, specifically the enzymatic cross-linking of collagen and elastin. Lysyl oxidase activity appears to be influenced directly by the amount of dietary copper over a wide physiological range of intakes, and therefore copper is essential in connective tissue health. Zinc is required by over 300 enzymes in the body for optimal activity, and many of these deal with nucleic acid synthesis, protein metabolism and connective tissue repair and maintenance.*

Zinc, Copper and Manganese have been shown to induce the production of SOD (superoxide dismutase), which converts damaging superoxide free radicals into hydrogen, which is further catabolized by catalase to water and oxygen. *

Glucosamine Sulfate and Chondroitin Sulfate are substances for the synthesis of GAG's (glycosaminoglycans or mucopolysaccharides) and PG's (proteoglycans), which are part of the basement membranes of connective tissue (e.g. skin and internal epithelia, intima of blood vessels, the heart valves, the lens and sclera of the eye, the synovial fluid and linings of joints) help form the "scaffolding" for protein and water chains and molecules that make up joints and connective tissue. They function in the homeostatic process of:  cell adhesion, motility, aggregation tissue morphogenesis and renewal, growth factor effects, angiogenesis, and in inflammatory cascade modulation.  It is the gel-like proteoglycans that give connective tissue its compressional strength and resiliency.*

N-Acetyl-D-Glucosamine is one of the disaccharides that makes up hyaluronic acid, a mucopolysaccharide that forms the backbone of proteoglycans and is a major component of synovial fluid and also acts as a free radical scavenger in synovial tissues. *

Selenium and Vitamin E work synergistically in replenishing key antioxidant systems (e.g. glutathione peroxidase) vital in inflammatory modulation and repair. *

Magnesium and Calcium regulate cell trafficking of nutrients and wastes and help regulate cellular energy mechanisms vital for connective tissue maintenance and repair.*

Bromelain is an enzyme derived from pineapple that has systemic proteolytic activity, which helps the body's repair mechanisms restructure and remodel connective tissue with an enhanced ability, at an accelerated rate.* Bromelain also supports the regulation of inflammation.*

Overall, Matrixx™ provides intelligent, comprehensive and sophisticated nutritional support to assist the body's maintenance and repair of connective tissue.*

References available upon request.

Allergy Research Group®, Inc.

*Any statements on Natural Health DOC relating to these products from Allergy Research Group® products have not been evaluated by the Food & Drug Administration. These product from Allergy Research Group ® are not intended to diagnose, treat, cure or prevent any disease.  All Trademarks "™" or Registered Marks "®"on these pages are the sole property of Allergy Research Group®

Disclaimers:
While we carry Allergy Research Group® products, neither A Natural Health Clinic, Inc., Natural Health DOC, or Dr. Linda Hadley nor any third party associated with us, related to or linked to Natural Health DOC, or any other affiliated business or website is in any way affiliated with Allergy Research Group®. Allergy Research Group® expressly disclaims any responsibility for and makes no representations or warranties regarding any statement, information, materials, or content found on or included in Dr. Linda Hadley's marketing materials, website, or any third party marketing materials or websites related to, associated with or linked to Natural Health DOC.

The products and claims made about specific products on their pages or their associated information sheets in or throughout Natural Health DOC or any of its affiliate websites, have not been evaluated by the Food & Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. The information presented in this website is for the purpose of "information only" and is not intended as a substitute for advice from a health care practitioner. Before starting any weight loss program, exercise program, diet, or supplements you should consult with a health care practitioner if you have or suspect you have a health issue.